One-Way Sensitivity Analysis

We conducted two sensitivity analyses to investigate the impact of parameter uncertainty on overall results. In a one-way sensitivity analysis, we varied a single parameter between a low to high range based on the 95% confidence interval of the parameter estimate where available and a 50% range where a confidence interval was not available. Total cost estimates based on the one-way sensitivity analyses are listed in Table 16.1 and Figure 12. Figure 13 shows the results of one-way sensitivity analysis for QALY and DALY losses.

Table 16.1. Impact on Overall Burden of Variation in Individual Parameters, total burden in $ billions

Impact on Overall Burden of Variation in Individual Parameters, total burden in $ billions

Figure 12. Tornado Diagram of One-way Sensitivity Analysis Results, Range of Economic Burden Associated with Range of each Parameter, $bn

Tornado Diagram of One-way Sensitivity Analysis Results, Range of Economic Burden Associated with Range of each Parameter, $bn

Figure 13. Tornado Diagram of One-way Sensitivity Analysis Results for QALY and DALY Losses

Tornado Diagram of One-way Sensitivity Analysis Results for QALY and DALY Losses