Impact of Parameter Uncertainty
We also conducted a one-way sensitivity analysis in which we measured the impact on the total economic burden estimates from changing individual parameters. We changed parameter values within their 95% confidence interval where available, or a 50%-150% range where not available. Results are most sensitive to the prevalence of visual loss, the impact on wages of vision loss, the cost of diagnosed disorders, the prevalence of visually impaired and blind persons in nursing homes, and the cost of undiagnosed vision loss. No other individual parameter or parameter group caused substantial changes in the overall estimate.